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Augmentin vs Levaquin

Created: June 10, 2009, Updated: June 11, 2014, Owner: claim ownershipPut your name here Comments (0)


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Amoxicillin/clavulanic acid (INN) or co-amoxiclav (BAN) is an antibiotic useful for the treatment of a number of bacterial infections. It is a combination antibiotic consisting of amoxicillin trihydrate, a β-lactam antibiotic, and potassium clavulanate, a β-lactamase inhibitor. This combination results in an antibiotic with an increased spectrum of action and restored efficacy against amoxicillin-resistant bacteria that produce β-lactamase. –Editor's choicemore
Levofloxacin (trade names Levaquin (US), Tavanic (EU), and others) is a broad spectrum antibiotic of the fluoroquinolone drug class, and the levo isomer of its predecessor ofloxacin. Its spectrum of activity includes most strains of bacterial pathogens responsible for respiratory, urinary tract, gastrointestinal, and abdominal infections, including Gram negative (Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Legionella pneumophila, Moraxella catarrhalis, Proteus mirabilis, and Pseudomonas aeruginosa), Gram positive (methicillin-sensitive but not methicillin-resistant Staphylococcus aureus, Streptococcus pneumoniae, Staphylococcus epidermidis, Enterococcus faecalis, and Streptococcus pyogenes), and atypical bacterial pathogens (Chlamydophila pneumoniae and Mycoplasma pneumoniae). Compared to earlier antibiotics of the fluoroquinoline class such as ciprofloxacin, levofloxacin exhibits greater activity toward Gram-(+) bacteria but lesser activity toward Gram-(−) bacteria, especially Pseudomonas aeruginosa. Levofloxacin and later generation fluoroquinolones are collectively referred to as "respiratory quinolones" to distinguish them from earlier fluoroquinolones which exhibited modest activity toward the important respiratory pathogen Streptococcus pneumoniae. –Editor's choicemore
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Trade namesAugmentin, Clavamox, TyclavLevaquin, Tavanic, Iquix (IV), Quixin (eye drops)
Licence dataUS FDA:linkUS FDA:link
Pregnancy cat.B1 (AU) B (US)C (US)
Legal statusPrescription Only (S4) (AU) ℞-only (CA) POM (UK) ℞-only (US)℞ Prescription only
Routesoral, intravenousOral, IV, ophthalmic
CAS number74469-00-4100986-85-4
ATC codeJ01CR02J01MA12 S01AE05
PubChemCID 6435923CID 149096
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