This combat page has no owner yet. You can claim ownershipclaim ownership to make it yours. It's free and grants privileges 


LAMICTAL vs Neurontin

Created: August 06, 2009, Updated: June 07, 2014, Owner: claim ownershipPut your name here Comments (0)


Upvoted 9 times [Upvoteupvote]


Upvoted 10 times [Upvoteupvote]
Lamotrigine /ləˈmoʊtrɨˌdʒiːn/, marketed in most of the world as Lamictal /ləˈmɪktəl/ by GlaxoSmithKline, is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. It is also used off-label as an adjunct in treating clinical depression. For epilepsy, it is used to treat focal seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Like many other anticonvulsant medications, lamotrigine also seems to act as an effective mood stabilizer, and has been the first US Food and Drug Administration (FDA)-approved drug for this purpose since lithium, a drug approved almost 30 years earlier. It is approved for the maintenance treatment of bipolar type I. Chemically unrelated to other anticonvulsants (due to lamotrigine being a phenyltriazine), lamotrigine has many possible side-effects. Lamotrigine is generally accepted to be a member of the sodium channel blocking class of antiepileptic drugs, but it could have additional actions since it has a broader spectrum of action than other sodium channel antiepileptic drugs such as phenytoin and carbamazepine and is effective in the treatment of the depressed phase of bipolar disorder, where as other sodium channel blocking antiepileptic drugs are not. In addition, lamotrigine shares few side-effects with other, unrelated anticonvulsants known to inhibit sodium channels, which further emphasises its unique properties. Lamotrigine is inactivated by hepatic glucuronidation. –Editor's choicemore
Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analog. It was originally developed to treat epilepsy, and currently is also used to relieve neuropathic pain. It is recommended as a first line agent for the treatment of neuropathic pain arising from diabetic neuropathy, post-herpetic neuralgia, and central neuropathic pain. –Editor's choicemore
Good sides
(advantages, pros)
Nothing's here. Be so nice and [Add newAdd new]
Hmmm, empty. We know you can [Add newAdd new]
Bad sides
(disadvantages, cons)
This cell is empty as... something empty. Be the one to [Add newAdd new]
Nothing's here. Don't be shy and [Add newAdd new]
Trade namesLamictalFanatrex, Gabarone, Gralise, Neurontin, Nupentin, Neogab
Licence dataUS FDA:linkUS Daily Med:link
Pregnancy cat.D (AU) C (US)B1 (AU) C (US)
Legal statusPrescription Only (S4) (AU) ℞-only (CA) POM (UK) ℞-only (US)Prescription Only (S4) (AU) ℞-only (CA) POM (UK) ℞-only (US)
Bioavailability98%27-60% (inversely proportional to dose; a high fat meal also increases bioavailability)
Protein binding55%Less than 3%
MetabolismHepatic (mostly UGT1A4-mediated)Not significantly metabolised
Half-life29 hours5 to 7 hours
ExcretionUrine (65%), faeces (2%)Renal
CAS number84057-84-160142-96-3
ATC codeN03AX09N03AX12
PubChemCID 3878CID 3446
Mol. mass256.091 g/mol171.237 g/mol
Read news about LAMICTAL
Search Wikipedia for LAMICTAL
Read news about Neurontin
Search Wikipedia for Neurontin

Warning: fopen(queryCache/8f9e4f6c3cb1a3c22d97ea8548176c92.txt): failed to open stream: Disk quota exceeded in /home/giftoget/public_html/ on line 140

Warning: flock() expects parameter 1 to be resource, boolean given in /home/giftoget/public_html/ on line 141

Warning: fwrite() expects parameter 1 to be resource, boolean given in /home/giftoget/public_html/ on line 142

Warning: fclose() expects parameter 1 to be resource, boolean given in /home/giftoget/public_html/ on line 143
Related combats:
Back to the combat pageTrileptal vs LAMICTALBack to the combat pageDilantin vs LAMICTALBack to the combat pageLAMICTAL vs Topamax
Back to the combat pageDepakote vs LAMICTALBack to the combat pageLithium vs LAMICTALBack to the combat pageKeppra vs LAMICTAL
Back to the combat pageCymbalta vs NeurontinBack to the combat pageGabapentin vs NeurontinBack to the combat pageKlonopin vs Neurontin
Back to the combat pageTopamax vs NeurontinBack to the combat pageVicodin vs NeurontinBack to the combat pageLamotrigine vs LAMICTAL

© 2007–2014 LASTCOMBAT


Warning: Unknown: open(/tmp/sess_3aed46c7bb17a20d64a5203ff7a8d487, O_RDWR) failed: Disk quota exceeded (122) in Unknown on line 0

Warning: Unknown: Failed to write session data (files). Please verify that the current setting of session.save_path is correct (/tmp) in Unknown on line 0